James Rowe

Visiting Professor

Research Interests

I work for the better understanding, diagnosis and treatment of degenerative brain diseases, including dementia and parkinsonian disorders. With my UK based group, we bring together computational models of brain and behaviour, physiology (MEG), structural and functional brain imaging (3T and 7T), and biomarkers of pathology (PET/blood), genetics and experimental treatments. I am here on sabbatical, having enjoyed working at DRCMR before, in 2004 and 2019.

Contact Details

James Rowe

Visiting Professor

jamesr@drcmr.dk

Affiliations

University of Copenhagen and University of Cambridge

Employments

2020 – Present

Associate Director, Dementia Platform UK

2020 – Present

Chief Scientific Advisor, Alzheimer Research UK

2015 – Present

Professor of Cognitive Neurology, Cambridge University

2015 – Present

Affiliated Professor of Clincial Neuroscience, Copenhagen

2013 – Present

Cambridge University Hospitals NHS Trust Dementia Lead

2010 – 2015

Reader in Cognitive Neurology, University of Cambridge

2009 – 2021

Wellcome Trust Senior Research Fellow in Clinical Science

2009 – Present

Program Leader, MRC Cognition and Brain Sciences Unit

2005 – Present

Consultant Neurologist, Addenbrooke's Hospital, Cambridge

2005 – 2009

Wellcome Trust Clinical Research Fellow

2004 – 2005

DRCMR Postdoc and Reservelæge, Rigshospitalet

Education

2012

FRCP, London

2005

CCT Neurology

2001

PhD in Neuroscience, UCL

1997

MRCP

1994

BM BCh in Medicine, University of Oxford

1991

BSc in Experimental Psychology, University of Cambridge

Publications

[620c0cf0-2e1c-4a0e-8a15-7ea0f13c0ed8 07dbffd2-79d9-43a4-ab98-be7a97d50d09 aca28f0a-ecf9-41d5-b801-90ee952ceb8b e8e401c0-a025-4875-83d5-89141dd82933 c71ae103-3f09-4ce5-a303-9bf100798831 d7014ac4-f9ce-407a-ba74-64be3c0675d1]

Kaalund SS, Passamonti L, Allinson KSJ, Murley AG, Robbins TW, Spillantini MG & Rowe JB, Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity

[map[#text:Acta neuropathologica communications -lang:en] map[#text:Acta Neuropathol Commun -lang:en]] 

  vol 8, Issue 1, p. 1-11, (2020). DOI:10.1186/s40478-020-0886-0

Correia MM, Rittman T, Barnes CL, Coyle-Gilchrist IT, Ghosh B, Hughes LE & Rowe JB, Towards accurate and unbiased imaging-based differentiation of Parkinson's disease, progressive supranuclear palsy and corticobasal syndrome

map[#text:Brain communications -lang:en] 

Brain communications  vol 2, Issue 1, p. 1-18, (2020). DOI:10.1093/braincomms/fcaa051

Düzel E, Acosta-Cabronero J, Berron D, Biessels GJ, Björkman-Burtscher I, Bottlaender M, Bowtell R, Buchem MV, Cardenas-Blanco A, Boumezbeur F, Chan D, Clare S, Costagli M, de Rochefort L, Fillmer A, Gowland P, Hansson O, Hendrikse J, Kraff O, Ladd ME, Ronen I, Petersen E, Rowe JB, Siebner H, Stoecker T, Straub S, Tosetti M, Uludag K, Vignaud A, Zwanenburg J & Speck O, European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)

[map[#text:Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring -lang:en] map[#text:Alzheimer's & dementia (Amsterdam, Netherlands) -lang:en] map[#text:Alzheimers Dement (Amst) -lang:en]] 

  vol 11, p. 538-549, (2019). DOI:10.1016/j.dadm.2019.04.010

van Eimeren T, Antonini A, Berg D, Bohnen N, Ceravolo R, Drzezga A, Höglinger GU, Higuchi M, Lehericy S, Lewis S, Monchi O, Nestor P, Ondrus M, Pavese N, Peralta MC, Piccini P, Pineda-Pardo JÁ, Rektorová I, Rodríguez-Oroz M, Rominger A, Seppi K, Stoessl AJ, Tessitore A, Thobois S, Kaasinen V, Wenning G, Siebner HR, Strafella AP & Rowe JB, Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System,

[map[#text:Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring -lang:en] map[#text:Alzheimer's & dementia (Amsterdam, Netherlands) -lang:en] map[#text:Alzheimers Dement (Amst) -lang:en]] 

  vol 11, p. 301-309, (2019). DOI:10.1016/j.dadm.2019.01.011

Betts MJ, Kirilina E, Otaduy MCG, Ivanov D, Acosta-Cabronero J, Callaghan MF, Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu KY, Priovoulos N, Fliessbach K, Dahl MJ, Maaß A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner HR, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E & Hämmerer D, Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

[map[#text:Brain -lang:en] map[#text:Brain -lang:en] map[#text:Brain : a journal of neurology -lang:en]] 

  vol 142, Issue 9, p. 2558-2571, (2019). DOI:10.1093/brain/awz193

Hornboll B, Macoveanu J, Nejad A, Rowe J, Elliott R, Knudsen GM, Siebner HR & Paulson OB, Neuroticism predicts the impact of serotonin challenges on fear processing in subgenual anterior cingulate cortex

[map[#text:Scientific Reports -lang:en] map[#text:Scientific Reports -lang:en]] 

  vol 8, Issue 1, p. 17889-17889, (2018). DOI:10.1038/s41598-018-36350-y

Lehéricy S, Vaillancourt DE, Seppi K, Monchi O, Rektorova I, Antonini A, McKeown MJ, Masellis M, Berg D, Rowe JB, Lewis SJG, Williams-Gray CH, Tessitore A & Siebner HR, The role of high-field magnetic resonance imaging in parkinsonian disorders: Pushing the boundaries forward,

[map[#text:Movement Disorders -lang:en] map[#text:Movement disorders : official journal of the Movement Disorder Society -lang:en]] 

  vol 32, Issue 4, p. 510-525, (2017). DOI:10.1002/mds.26968

Herz DM, Haagensen BN, Christensen MS, Madsen KH, Rowe JB, Løkkegaard A & Siebner HR, Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans

[map[#text:Brain -lang:en] map[#text:Brain -lang:en] map[#text:Brain : a journal of neurology -lang:en]] 

  vol 138, Issue Pt 6, p. 1658-1666, (2015). DOI:10.1093/brain/awv096

Herz DM, Haagensen BN, Christensen MS, Madsen KH, Rowe JB, Løkkegaard A & Siebner HR, The acute brain response to levodopa heralds dyskinesias in Parkinson disease

map[#text:Annals of Neurology -lang:en] 

Annals of Neurology  vol 75, Issue 6, p. 829-836, (2014). DOI:10.1002/ana.24138

Wolpe N, Haggard P, Siebner HR & Rowe JB, Cue integration and the perception of action in intentional binding

map[#text:Experimental Brain Research -lang:en] 

Experimental Brain Research  vol 229, Issue 3, p. 467-474, (2013). DOI:10.1007/s00221-013-3419-2

Macoveanu J, Rowe JB, Hornboll B, Elliott R, Paulson OB, Knudsen GM & Siebner HR, Playing it safe but losing anyway-Serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion

[map[#text:European Neuropsychopharmacology -lang:en] map[#text:European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology -lang:en] map[#text:Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology -lang:en] map[#text:Journal of European College of Neuropsychopharmacology -lang:en]] 

  vol 23, Issue 8, p. 919-930, (2013). DOI:10.1016/j.euroneuro.2012.09.006

Rowe JB & Siebner HR, The motor system and its disorders

map[#text:NeuroImage -lang:en] 

NeuroImage  vol 61, Issue 2, p. 464-477, (2012). DOI:10.1016/j.neuroimage.2011.12.042

Christensen MS, Kristiansen L, Rowe JB & Nielsen JB, Action-blindsight in healthy subjects after transcranial magnetic stimulation.

[map[#text:National Academy of Sciences. Proceedings -lang:en] map[#text:Proceedings of the National Academy of Sciences of the United States of America -lang:en]] 

  vol 105, Issue 4, p. 1353-1357, (2008). DOI:10.1073/pnas.0705858105

Korsholm K, Madsen K, Frederiksen JL, Rowe JB & Lund TE, Cortical neuroplasticity in patients recovering from acute optic neuritis

map[#text:NeuroImage -lang:en] 

NeuroImage  vol 42, Issue 2, p. 836-844, (2008). DOI:10.1016/j.neuroimage.2008.05.031

Christensen MS, Ramsøy TZ, Lund TE, Madsen K & Rowe JB, An fMRI study of the neural correlates of graded visual perception

map[#text:NeuroImage -lang:en] 

NeuroImage  vol 31, Issue 4, p. 1711-1725, (2006). DOI:10.1016/j.neuroimage.2006.02.023

Lund TE, Nørgaard MD, Rostrup E, Rowe JB & Paulson OB, Motion or activity: their role in intra- and inter-subject variation in fMRI.

map[#text:NeuroImage -lang:en] 

NeuroImage  vol 26, Issue 3, p. 960-964, (2005). DOI:10.1016/j.neuroimage.2005.02.021

Rowe JB, Stephan KE, Friston K, Frackowiak RS & Passingham RE, The prefrontal cortex shows context-specific changes in effective connectivity to motor or visual cortex during the selection of action or colour.

[map[#text:Cerebral Cortex -lang:en] map[#text:Cerebral Cortex -lang:en]] 

  vol 15, Issue 1, p. 85-95, (2005). DOI:


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