James Rowe

Visiting Professor

Research Interests

I work for the better understanding, diagnosis and treatment of degenerative brain diseases, including dementia and parkinsonian disorders. With my UK based group, we bring together computational models of brain and behaviour, physiology (MEG), structural and functional brain imaging (3T and 7T), and biomarkers of pathology (PET/blood), genetics and experimental treatments. I am here on sabbatical, having enjoyed working at DRCMR before, in 2004 and 2019.

Contact Details

James Rowe

Visiting Professor

jamesr@drcmr.dk

Affiliations

University of Copenhagen and University of Cambridge

Employments

2020 – Present

Associate Director, Dementia Platform UK

2020 – Present

Chief Scientific Advisor, Alzheimer Research UK

2015 – Present

Professor of Cognitive Neurology, Cambridge University

2015 – Present

Affiliated Professor of Clincial Neuroscience, Copenhagen

2013 – Present

Cambridge University Hospitals NHS Trust Dementia Lead

2010 – 2015

Reader in Cognitive Neurology, University of Cambridge

2009 – 2021

Wellcome Trust Senior Research Fellow in Clinical Science

2009 – Present

Program Leader, MRC Cognition and Brain Sciences Unit

2005 – Present

Consultant Neurologist, Addenbrooke's Hospital, Cambridge

2005 – 2009

Wellcome Trust Clinical Research Fellow

2004 – 2005

DRCMR Postdoc and Reservelæge, Rigshospitalet

Education

2012

FRCP, London

2005

CCT Neurology

2001

PhD in Neuroscience, UCL

1997

MRCP

1994

BM BCh in Medicine, University of Oxford

1991

BSc in Experimental Psychology, University of Cambridge

Publications

Kaalund SS, Passamonti L, Allinson KSJ, Murley AG, Robbins TW, Spillantini MG, Rowe JB (2020), 'Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity', Acta neuropathologica communications, 8(1):1-11


Correia MM, Rittman T, Barnes CL, Coyle-Gilchrist IT, Ghosh B, Hughes LE, Rowe JB (2020), 'Towards accurate and unbiased imaging-based differentiation of Parkinson's disease, progressive supranuclear palsy and corticobasal syndrome', Brain communications, 2(1):1-18


Düzel E, Acosta-Cabronero J, Berron D, Biessels GJ, Björkman-Burtscher I, Bottlaender M, Bowtell R, Buchem MV, Cardenas-Blanco A, Boumezbeur F, Chan D, Clare S, Costagli M, de Rochefort L, Fillmer A, Gowland P, Hansson O, Hendrikse J, Kraff O, Ladd ME, Ronen I, Petersen E, Rowe JB, Siebner H, Stoecker T, Straub S, Tosetti M, Uludag K, Vignaud A, Zwanenburg J, Speck O (2019), 'European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)', Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 11:538-549


van Eimeren T, Antonini A, Berg D, Bohnen N, Ceravolo R, Drzezga A, Höglinger GU, Higuchi M, Lehericy S, Lewis S, Monchi O, Nestor P, Ondrus M, Pavese N, Peralta MC, Piccini P, Pineda-Pardo JÁ, Rektorová I, Rodríguez-Oroz M, Rominger A, Seppi K, Stoessl AJ, Tessitore A, Thobois S, Kaasinen V, Wenning G, Siebner HR, Strafella AP, Rowe JB (2019), 'Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders', Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 11:301-309


Betts MJ, Kirilina E, Otaduy MCG, Ivanov D, Acosta-Cabronero J, Callaghan MF, Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu KY, Priovoulos N, Fliessbach K, Dahl MJ, Maaß A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner HR, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E, Hämmerer D (2019), 'Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases', Brain, 142(9):2558-2571


Dagher A, Lehéricy S, Rowe JB, Siebner HR (2019), unknown publication 18fc4598-3316-4d22-9fa0-6e026aac940e


Hornboll B, Macoveanu J, Nejad A, Rowe J, Elliott R, Knudsen GM, Siebner HR, Paulson OB (2018), 'Neuroticism predicts the impact of serotonin challenges on fear processing in subgenual anterior cingulate cortex', Scientific Reports, 8(1):17889


Lehéricy S, Vaillancourt DE, Seppi K, Monchi O, Rektorova I, Antonini A, McKeown MJ, Masellis M, Berg D, Rowe JB, Lewis SJG, Williams-Gray CH, Tessitore A, Siebner HR (2017), 'The role of high-field magnetic resonance imaging in parkinsonian disorders', Movement Disorders, 32(4):510-525


Herz DM, Haagensen BN, Christensen MS, Madsen KH, Rowe JB, Løkkegaard A, Siebner HR (2015), 'Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans', Brain, 138(Pt 6):1658-1666


Herz DM, Haagensen BN, Christensen MS, Madsen KH, Rowe JB, Løkkegaard A, Siebner HR (2014), 'The acute brain response to levodopa heralds dyskinesias in Parkinson disease', Annals of Neurology, 75(6):829-836


Siebner HR, Strafella AP, Rowe JB (2014), 'The white elephant revived: A new marriage between PET and MRI', NeuroImage, 84:1104-1106


Angstmann S, Zhang J, Hallsson B, Madsen KH, Rowe J, Siebner HR (2014), unknown publication dc9b2ceb-401a-455e-afcb-771ca8383fa6


Wolpe N, Haggard P, Siebner HR, Rowe JB (2013), 'Cue integration and the perception of action in intentional binding', Experimental Brain Research, 229(3):467-474


Macoveanu J, Rowe JB, Hornboll B, Elliott R, Paulson OB, Knudsen GM, Siebner HR (2013), 'Playing it safe but losing anyway-Serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion', European Neuropsychopharmacology, 23(8):919-930


Rowe JB, Siebner HR (2012), 'The motor system and its disorders', NeuroImage, 61(2):464-477


Macoveanu J, Rowe JB, Hornbøll B, Elliott R, Paulson OB, Knudsen GM, Siebner HR (2011), unknown publication aaacb847-6a70-49b8-a7e7-57f8320b5872


Macoveanu J, Hornbøll B, Knudsen GM, Paulson OB, Rowe JB, Siebner H (2009), unknown publication 5e073dac-bec2-4613-9752-d77ab2c20218


Christensen MS, Kristiansen L, Rowe JB, Nielsen JB (2008), 'Action-blindsight in healthy subjects after transcranial magnetic stimulation.', National Academy of Sciences. Proceedings, 105(4):1353-1357


Hornbøll B, Wegener J, Paulson OB, Rowe JB, Moos Knudsen G, Siebner H, Macoveanu J (2008), unknown publication a90ef4eb-f742-42cf-a8f7-7ba0690f5ce6


Korsholm K, Madsen K, Frederiksen JL, Rowe JB, Lund TE (2008), 'Cortical neuroplasticity in patients recovering from acute optic neuritis', NeuroImage, 42(2):836-844


Paulson OB, Macoveanu J, Wegener J, Skimminge A, Erritzoe D, Rowe J (2008), unknown publication cf1d7fb4-397c-4414-8747-f338d11db1a7


Christensen MS, Ramsøy TZ, Lund TE, Madsen K, Rowe JB (2006), 'An fMRI study of the neural correlates of graded visual perception', NeuroImage, 31(4):1711-1725


Lund TE, Nørgaard MD, Rostrup E, Rowe JB, Paulson OB (2005), 'Motion or activity: their role in intra- and inter-subject variation in fMRI.', NeuroImage, 26(3):960-964


Skov M, Christensen MS, Rowe J, Paulson OB (2005), unknown publication 3b919309-7d9b-406f-8c9d-f4fb202fd679


Rowe JB, Stephan KE, Friston K, Frackowiak RS, Passingham RE (2005), 'The prefrontal cortex shows context-specific changes in effective connectivity to motor or visual cortex during the selection of action or colour.', Cerebral Cortex, 15(1):85-95



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