Research Interests
Bayesian modeling, segmentation, structural MRI
DRCMR
Bayesian modeling, segmentation, structural MRI

DTU Elektro
2016 – Present | Postdoc, DRCMR and Technical University of Denmark |
2012 – 2016 | PhD student at Technical University of Denmark |
2013 – 2013 | Visiting Researcher, Aalto University Department of Information and Computer Science, Espoo, Finland |
2012 – 2012 | Visiting Researcher, Althinoula A. Martinos Center for Biomedical Imaging, Boston, USA |
2010 – 2012 | Research Assistant, Aalto University Department of Information and Computer Science, Espoo, Finland |
2009 – 2009 | Research Assistant, Brain Research Unit, Espoo, Finland |
2016 | PhD in Informatics, Technical University of Denmark |
2012 | MSc in Theoretical Physics, University of Helsinki |
2011 | BSc in Theoretical Physics, University of Helsinki |
Soleimani G, Alekseichuk I, Aurup C, Bergmann TO, Bestmann S, Beynel L, Evans C, Frohlich F, Ghobadi-Azbari P, Hanlon CA, Kasten F, Konofagou EE, Lueckel M, Márquez-Ruiz J, Mencarelli L, Mosayebi-Samani M, Neige C, Opitz A, Peterchev A, Puonti O, Sackeim HA, Sánchez-Garrido Campos G, Siebner HR, Thielscher A, Vlachos A, Voroslakos M, Nitsche MA, Lisanby SH, Bikson M and Ekhtiari H (2026), 'Dose-Response Relationships in Transcranial Brain Stimulation: Physics, Physiology and Mechanism', Brain Stimulation, 19(3), doi:10.1016/j.brs.2026.103067
Nielsen JD, Gopinath K, Hoopes A, Dalca A, Magdamo C, Arnold S, Das S, Thielscher A, Iglesias JE and Puonti O (2026), unknown publication d99ffd1e-0910-4c98-ae58-69192177f5c4, doi:10.1007/978-3-032-09513-8_21
Huertas-Penen S, Piastra MC, Puonti O and Schwab BC (2026), 'Variable E-field properties of dual-site tACS with phase lags', Imaging Neuroscience, 4, doi:10.1162/IMAG.a.1068
Casamitjana A, Mancini M, Robinson E, Peter L, Annunziata R, Althonayan J, Crampsie S, Blackburn E, Billot B, Atzeni A, Puonti O, Balbastre Y, Schmidt P, Hughes J, Augustinack JC, Edlow BL, Zöllei L, Thomas DL, Kliemann D, Bocchetta M, Strand C, Holton JL, Jaunmuktane Z and Iglesias JE (2024), 'A probabilistic histological atlas of the human brain for MRI segmentation', Nature, 648(8094):678-685, doi:10.1038/s41586-025-09708-2
Hu X, Zeng X, Puonti O, Iglesias JE, Fischl B and Balbastre Y (2025), unknown publication 3ede8321-f6bc-47ab-b0c8-58beee57181f
Puonti O, Nolan J, Dicamillo R, Balbastre Y, Casamitjana A, Mancini M, Robinson E, Peter L, Annunziata R, Althonayan J, Crampsie S, Blackburn E, Billot B, Atzeni A, Schmidt P, Hughes J, Augustinack J, Edlow B, Zöllei L, Thomas DL, Kliemann D, Bocchetta M, Strand C, Holton J, Jaunmuktane Z and Iglesias JE (2025), unknown publication c7a7b423-e9de-4383-bb35-4415b04955e4, doi:10.1101/2025.09.22.673638
Wiltgen T, McGinnis J, Berg R, Voon CC, Puonti O, Giglhuber K, Ganter C, Zimmer C, Hemmer B, Wiestler B, Kirschke J, Preibisch C and Mühlau M (2025), 'Towards quantitative intensity analysis of conventional T1-weighted images in multiple sclerosis', NeuroImage, 318, doi:10.1016/j.neuroimage.2025.121395
Diedrichsen M, Merhout J, Nielsen JD, Greve DN, Thielscher A and Puonti O (2025), unknown publication 8a977e15-b295-4520-91cb-f69ebdd8481a, doi:10.1109/EMBC58623.2025.11254267
Gopinath K, Greve DN, Magdamo C, Arnold S, Das S, Puonti O and Iglesias JE (2025), '“Recon-all-clinical”: Cortical surface reconstruction and analysis of heterogeneous clinical brain MRI', Medical Image Analysis, 103, doi:10.48550/arXiv.2409.03889
Cao F, Madsen KH, Worbs T, Puonti O, Siebner HR, Schmitgen A, Kunz P and Thielscher A (2025), 'Fast FEM-based electric field calculations for transcranial magnetic stimulation', Journal of Neural Engineering, 22(3), doi:10.1088/1741-2552/add76d
Hu X, Gopinath K, Liu P, Van Leemput K, Puonti O and Iglesias JE (2025), unknown publication b3f747dd-f6f7-42ac-853c-f5d25ee2c62b, doi:10.48550/arXiv.2410.09299
Mauri C, Cerri S, Puonti O, Mühlau M and Van Leemput K (2024), 'A lightweight generative model for interpretable subject-level prediction', Medical Image Analysis, 101, doi:10.1016/j.media.2024.103436
Zadeh AK, Puonti O, Sigurðsson B, Thielscher A, Monchi O and Pichardo S (2025), 'Enhancing transcranial ultrasound stimulation planning with MRI-derived skull masks: a comparative analysis with CT-based processing', Journal of Neural Engineering, 22(1), doi:10.1088/1741-2552/adab22
Van Hoornweder S, Cappozzo V, De Herde L, Puonti O, Siebner HR, Meesen R and Thielscher A (2024), 'Head and shoulders—The impact of an extended head model on the simulation and optimization of transcranial electric stimulation', Imaging Neuroscience, 2:1-11, doi:10.1162/imag_a_00379
Liu P, Puonti O, Hu X, Alexander DC and Iglesias JE (2024), unknown publication 7e8ed6a8-66bb-4ea2-a3cb-57eb81c396bf, doi:10.1007/978-3-031-73254-6_19
Gopinath K, Hoopes A, Alexander DC, Arnold SE, Billot B, Casamitjana A, Cheng Y, Chua RYZ, Edlow BL, Fischl B, Gazula H, Keene CD, Kim S, Kimberly WT, Laguna S, Larson KE, Leemput KV, Puonti O, Rodrigues L, Rosen M, Tregidgo HFJ, Varadarajan D, Young SI, Dalca AV and Iglesias JE (2024), 'Synthetic data in generalizable, learning-based neuroimaging', Imaging Neuroscience, 2:1-22, doi:10.1162/imag_a_00337
Gopinath K, Hu X, Hoffmann M, Puonti O and Iglesias JE (2024), unknown publication 1eca3a2c-67fb-4734-beb1-37110b215bf5, doi:10.1007/978-3-031-73480-9_16
Hu X, Sorby-Adams A, Barkhof F, Kimberly WT, Puonti O and Iglesias JE (2024), unknown publication c1d85fa5-7135-4183-8087-2e28f52aea4c, doi:10.1007/978-3-031-73967-5_10
Liu P, Puonti O, Sorby-Adams A, Kimberly WT and Iglesias JE (2024), unknown publication 6b84f33f-a8c4-485e-bc7b-8e5156656d13, doi:10.1007/978-3-031-72390-2_63
Zeng X, Puonti O, Sayeed A, Herisse R, Mora J, Evancic K, Varadarajan D, Balbastre Y, Costantini I, Scardigli M, Ramazzotti J, DiMeo D, Mazzamuto G, Pesce L, Brady N, Cheli F, Saverio Pavone F, Hof PR, Frost R, Augustinack J, Van der Kouwe A, Eugenio Iglesias J and Fischl B (2024), 'Segmentation of supragranular and infragranular layers in ultra-high-resolution 7T ex vivo MRI of the human cerebral cortex', Cerebral Cortex, 34(9):1-13, doi:10.1093/cercor/bhae362
Gurr C, Splittgerber M, Puonti O, Siemann J, Luckhardt C, Pereira HC, Amaral J, Crisóstomo J, Sayal A, Ribeiro M, Sousa D, Dempfle A, Krauel K, Borzikowsky C, Brauer H, Prehn-Kristensen A, Breitling-Ziegler C, Castelo-Branco M, Salvador R, Damiani G, Ruffini G, Siniatchkin M, Thielscher A, Freitag CM, Moliadze V and Ecker C (2024), 'Neuroanatomical Predictors of Transcranial Direct Current Stimulation (tDCS)-Induced Modifications in Neurocognitive Task Performance in Typically Developing Individuals', The Journal of Neuroscience, 44(22):1-12
Laso P, Cerri S, Sorby-Adams A, Guo J, Mateen F, Goebl P, Wu J, Liu P, Li H, Young SI, Billot B, Puonti O, Sze G, Payabavash S, DeHavenon A, Sheth K, Rosen M, Kirsch J, Strisciuglio N, Wolterink JM, Eshaghi A, Barkhof F, Kimberly WT and Iglesias JE (2024), unknown publication 3cc10030-55d5-48b9-8a58-80b79860dc74, doi:10.1109/ISBI56570.2024.10635502
Fuglsang SA, Madsen KH, Puonti O, Siebner HR and Hjortkjær J (2024), 'Exploring an EM-algorithm for banded regression in computational neuroscience', Imaging Neuroscience, 2:1-19, doi:10.1162/imag_a_00155
Gregersen F, Eroğlu HH, Göksu C, Puonti O, Zuo Z, Thielscher A and Hanson L (2024), 'MR imaging of the magnetic fields induced by injected currents can guide improvements of individualized head volume conductor models', Imaging Neuroscience, 2:1-15, doi:10.1162/imag_a_00176
Mantell KE, Perera ND, Shirinpour S, Puonti O, Xu T, Zimmermann J, Falchier A, Heilbronner SR, Thielscher A and Opitz A (2023), 'Anatomical details affect electric field predictions for non-invasive brain stimulation in non-human primates', NeuroImage, 279:1-12, doi:10.1016/j.neuroimage.2023.120343
Hosseini S, Puonti O, Treeby B, Hanson LG and Thielscher A (2023), 'A Head Template for Computational Dose Modelling for Transcranial Focused Ultrasound Stimulation', NeuroImage, 277:1-14, doi:10.1016/j.neuroimage.2023.120227
Nielsen JD, Puonti O, Xue R, Thielscher A and Madsen KH (2023), 'Evaluating the Influence of Anatomical Accuracy and Electrode Positions on EEG Forward Solutions', NeuroImage, 277:1-20, doi:10.1016/j.neuroimage.2023.120259
Madsen MAJ, Wiggermann V, Marques MFM, Lundell H, Cerri S, Puonti O, Blinkenberg M, Christensen JR, Sellebjerg F and Siebner HR (2022), 'Linking lesions in sensorimotor cortex to contralateral hand function in multiple sclerosis: a 7 T MRI study', Brain, 145(10):3522-3535, doi:10.1093/brain/awac203
Mauri C, Cerri S, Puonti O, Mühlau M and Van Leemput K (2022), unknown publication 82b7d4ee-5281-46e1-b10b-d500c9abdc52, doi:10.1007/978-3-031-16452-1_43
Nandi T, Puonti O, Clarke WT, Nettekoven C, Barron HC, Kolasinski J, Hanayik T, Hinson EL, Berrington A, Bachtiar V, Johnstone A, Winkler AM, Thielscher A, Johansen-Berg H and Stagg CJ (2022), 'tDCS induced GABA change is associated with the simulated electric field in M1, an effect mediated by grey matter volume in the MRS voxel', Brain Stimulation, 15(5):1153-1162, doi:10.1016/j.brs.2022.07.049
Fuglsang SA, Madsen KH, Puonti O, Hjortkjær J and Siebner HR (2021), 'Mapping cortico-subcortical sensitivity to 4 Hz amplitude modulation depth in human auditory system with functional MRI', NeuroImage, 246:1-12, doi:10.1016/j.neuroimage.2021.118745
Splittgerber M, Borzikowsky C, Salvador R, Puonti O, Papadimitriou K, Merschformann C, Biagi MC, Stenner T, Brauer H, Breitling-Ziegler C, Prehn-Kristensen A, Krauel K, Ruffini G, Pedersen A, Nees F, Thielscher A, Dempfle A, Siniatchkin M and Moliadze V (2021), 'Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population', Scientific Reports, 11(1):1-15, doi:10.1038/s41598-021-00933-z
Shirinpour S, Mantell K, Li X, Puonti O, Madsen K, Haigh Z, Casillo EC, Alekseichuk I, Hendrickson T and Xu T (2021), 'New tools for computational modeling of non-invasive brain stimulation in SimNIBS', Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 14(6):1644, doi:10.1016/j.brs.2021.10.180
Eroğlu HH, Puonti O, Göksu C, Gregersen F, Siebner HR, Hanson LG and Thielscher A (2021), 'On the reconstruction of magnetic resonance current density images of the human brain: Pitfalls and perspectives', NeuroImage, 243:1-15, doi:10.1016/j.neuroimage.2021.118517
Antonenko D, Grittner U, Puonti O, Flöel A and Thielscher A (2021), 'Estimation of individually induced e-field strength during transcranial electric stimulation using the head circumference', Brain Stimulation, 14(5):1055-1058, doi:10.1016/j.brs.2021.07.001
Cerri S, Puonti O, Meier DS, Wuerfel J, Mühlau M, Siebner HR and Leemput KV (2020), 'A Contrast-Adaptive Method for Simultaneous Whole-Brain and Lesion Segmentation in Multiple Sclerosis', NeuroImage, 225:1-17, doi:10.1016/j.neuroimage.2020.117471
Puonti O, Van Leemput K, Saturnino GB, Siebner HR, Madsen KH and Thielscher A (2020), 'Accurate and robust whole-head segmentation from magnetic resonance images for individualized head modeling', NeuroImage, 219:1-17, doi:10.1016/j.neuroimage.2020.117044
Puonti O, Saturnino GB, Madsen KH and Thielscher A (2019), 'Value and limitations of intracranial recordings for validating electric field modeling for transcranial brain stimulation', NeuroImage, 208:1-14, doi:10.1016/j.neuroimage.2019.116431
Hougaard A, Nielsen SH, Gaist D, Puonti O, Garde E, Reislev NL, Iversen P, Madsen CG, Blaabjerg M, Nielsen HH, Krøigård T, Østergaard K, Kyvik KO, Madsen KH, Siebner HR and Ashina M (2020), 'Migraine with aura in women is not associated with structural thalamic abnormalities', NeuroImage: Clinical, 28, doi:10.1016/j.nicl.2020.102361
Opheim G, Puonti O, Pedersen JO, Boer VO, Kloster A, Prener M, Simonsen HJ, Paulson OB, Pinborg LH and Ganz M (2020), unknown publication 46afb1a9-c226-4154-80c6-d9774c2c6f8d
Salvador R, Biagi MC, Puonti O, Splittgerber M, Moliadze V, Siniatchkin M, Thielscher A and Ruffini G (2020), unknown publication 94fdb946-4b4b-4a52-98c8-a4ad3ad7a43b, doi:10.1007/978-3-030-45623-8_7
Andreasen SH, Andersen KW, Conde V, Dyrby TB, Puonti O, Kammersgaard LP, Madsen CG, Madsen KH, Poulsen I and Siebner HR (2020), 'Two Coarse Spatial Patterns of Altered Brain Microstructure Predict Post-traumatic Amnesia in the Subacute Stage of Severe Traumatic Brain Injury', Frontiers in Neurology, 11:1-14, doi:10.3389/fneur.2020.00800
Agn M, Munck Af Rosenschöld P, Puonti O, Lundemann MJ, Mancini L, Papadaki A, Thust S, Ashburner J, Law I and Van Leemput K (2019), 'A modality-adaptive method for segmenting brain tumors and organs-at-risk in radiation therapy planning', Medical Image Analysis, 54:220-237, doi:10.1016/j.media.2019.03.005
Farcito S, Puonti O, Montanaro H, Saturnino GB, Nielsen JD, Madsen CG, Siebner HR, Neufeld E, Kuster N, Lloyd BA and Thielscher A (2019), unknown publication 2feb9c9f-a5e4-485d-802f-a010cbfa4f9e, doi:10.1109/EMBC.2019.8857041
Saturnino GB, Puonti O, Nielsen JD, Antonenko D, Madsen KH and Thielscher A (2019), unknown publication 1c41e689-ec5e-49e8-8b86-e031e888595b, doi:10.1007/978-3-030-21293-3_1
Boayue NM, Csifcsák G, Puonti O, Thielscher A and Mittner M (2018), 'Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation', F1000Research, 7:704, doi:10.12688/f1000research.15125.2
Nielsen JD, Madsen KH, Puonti O, Siebner HR, Bauer C, Madsen CG, Saturnino GB and Thielscher A (2018), 'Automatic skull segmentation from MR images for realistic volume conductor models of the head: Assessment of the state-of-the-art', NeuroImage, 174:587-598, doi:10.1016/j.neuroimage.2018.03.001
Csifcsák G, Boayue NM, Puonti O, Thielscher A and Mittner M (2018), 'Effects of transcranial direct current stimulation for treating depression: A modeling study', Journal of Affective Disorders, 234:164-173, doi:10.1016/j.jad.2018.02.077
Cid YD, Puonti O, Platon A, Van Leemput K, Müller H and Poletti PA (2018), unknown publication ff703b89-0d9c-4e34-9255-c7d6a752acb9, doi:10.1117/12.2294004
Puonti O, Van Leemput K, Nielsen JD, Bauer C, Siebner HR, Madsen KH and Thielscher A (2018), unknown publication 0241e401-b1ca-410e-8d99-70a2a0d51499, doi:10.1117/12.2293073