Oula Puonti

Research Fellow

Employments

2016 – Present

Postdoc, DRCMR and Technical University of Denmark

2012 – 2016

PhD student at Technical University of Denmark

2013 – 2013

Visiting Researcher, Aalto University Department of Information and Computer Science, Espoo, Finland

2012 – 2012

Visiting Researcher, Althinoula A. Martinos Center for Biomedical Imaging, Boston, USA

2010 – 2012

Research Assistant, Aalto University Department of Information and Computer Science, Espoo, Finland

2009 – 2009

Research Assistant, Brain Research Unit, Espoo, Finland

Education

2016

PhD in Informatics, Technical University of Denmark

2012

MSc in Theoretical Physics, University of Helsinki

2011

BSc in Theoretical Physics, University of Helsinki

Publications

Soleimani G, Alekseichuk I, Aurup C, Bergmann TO, Bestmann S, Beynel L, Evans C, Frohlich F, Ghobadi-Azbari P, Hanlon CA, Kasten F, Konofagou EE, Lueckel M, Márquez-Ruiz J, Mencarelli L, Mosayebi-Samani M, Neige C, Opitz A, Peterchev A, Puonti O, Sackeim HA, Sánchez-Garrido Campos G, Siebner HR, Thielscher A, Vlachos A, Voroslakos M, Nitsche MA, Lisanby SH, Bikson M and Ekhtiari H (2026), 'Dose-Response Relationships in Transcranial Brain Stimulation: Physics, Physiology and Mechanism', Brain Stimulation, 19(3), doi:10.1016/j.brs.2026.103067

Nielsen JD, Gopinath K, Hoopes A, Dalca A, Magdamo C, Arnold S, Das S, Thielscher A, Iglesias JE and Puonti O (2026), unknown publication d99ffd1e-0910-4c98-ae58-69192177f5c4, doi:10.1007/978-3-032-09513-8_21

Huertas-Penen S, Piastra MC, Puonti O and Schwab BC (2026), 'Variable E-field properties of dual-site tACS with phase lags', Imaging Neuroscience, 4, doi:10.1162/IMAG.a.1068

Casamitjana A, Mancini M, Robinson E, Peter L, Annunziata R, Althonayan J, Crampsie S, Blackburn E, Billot B, Atzeni A, Puonti O, Balbastre Y, Schmidt P, Hughes J, Augustinack JC, Edlow BL, Zöllei L, Thomas DL, Kliemann D, Bocchetta M, Strand C, Holton JL, Jaunmuktane Z and Iglesias JE (2024), 'A probabilistic histological atlas of the human brain for MRI segmentation', Nature, 648(8094):678-685, doi:10.1038/s41586-025-09708-2

Hu X, Zeng X, Puonti O, Iglesias JE, Fischl B and Balbastre Y (2025), unknown publication 3ede8321-f6bc-47ab-b0c8-58beee57181f

Puonti O, Nolan J, Dicamillo R, Balbastre Y, Casamitjana A, Mancini M, Robinson E, Peter L, Annunziata R, Althonayan J, Crampsie S, Blackburn E, Billot B, Atzeni A, Schmidt P, Hughes J, Augustinack J, Edlow B, Zöllei L, Thomas DL, Kliemann D, Bocchetta M, Strand C, Holton J, Jaunmuktane Z and Iglesias JE (2025), unknown publication c7a7b423-e9de-4383-bb35-4415b04955e4, doi:10.1101/2025.09.22.673638

Wiltgen T, McGinnis J, Berg R, Voon CC, Puonti O, Giglhuber K, Ganter C, Zimmer C, Hemmer B, Wiestler B, Kirschke J, Preibisch C and Mühlau M (2025), 'Towards quantitative intensity analysis of conventional T1-weighted images in multiple sclerosis', NeuroImage, 318, doi:10.1016/j.neuroimage.2025.121395

Diedrichsen M, Merhout J, Nielsen JD, Greve DN, Thielscher A and Puonti O (2025), unknown publication 8a977e15-b295-4520-91cb-f69ebdd8481a, doi:10.1109/EMBC58623.2025.11254267

Gopinath K, Greve DN, Magdamo C, Arnold S, Das S, Puonti O and Iglesias JE (2025), '“Recon-all-clinical”: Cortical surface reconstruction and analysis of heterogeneous clinical brain MRI', Medical Image Analysis, 103, doi:10.48550/arXiv.2409.03889

Cao F, Madsen KH, Worbs T, Puonti O, Siebner HR, Schmitgen A, Kunz P and Thielscher A (2025), 'Fast FEM-based electric field calculations for transcranial magnetic stimulation', Journal of Neural Engineering, 22(3), doi:10.1088/1741-2552/add76d

Hu X, Gopinath K, Liu P, Van Leemput K, Puonti O and Iglesias JE (2025), unknown publication b3f747dd-f6f7-42ac-853c-f5d25ee2c62b, doi:10.48550/arXiv.2410.09299

Mauri C, Cerri S, Puonti O, Mühlau M and Van Leemput K (2024), 'A lightweight generative model for interpretable subject-level prediction', Medical Image Analysis, 101, doi:10.1016/j.media.2024.103436

Zadeh AK, Puonti O, Sigurðsson B, Thielscher A, Monchi O and Pichardo S (2025), 'Enhancing transcranial ultrasound stimulation planning with MRI-derived skull masks: a comparative analysis with CT-based processing', Journal of Neural Engineering, 22(1), doi:10.1088/1741-2552/adab22

Van Hoornweder S, Cappozzo V, De Herde L, Puonti O, Siebner HR, Meesen R and Thielscher A (2024), 'Head and shoulders—The impact of an extended head model on the simulation and optimization of transcranial electric stimulation', Imaging Neuroscience, 2:1-11, doi:10.1162/imag_a_00379

Liu P, Puonti O, Hu X, Alexander DC and Iglesias JE (2024), unknown publication 7e8ed6a8-66bb-4ea2-a3cb-57eb81c396bf, doi:10.1007/978-3-031-73254-6_19

Gopinath K, Hoopes A, Alexander DC, Arnold SE, Billot B, Casamitjana A, Cheng Y, Chua RYZ, Edlow BL, Fischl B, Gazula H, Keene CD, Kim S, Kimberly WT, Laguna S, Larson KE, Leemput KV, Puonti O, Rodrigues L, Rosen M, Tregidgo HFJ, Varadarajan D, Young SI, Dalca AV and Iglesias JE (2024), 'Synthetic data in generalizable, learning-based neuroimaging', Imaging Neuroscience, 2:1-22, doi:10.1162/imag_a_00337

Gopinath K, Hu X, Hoffmann M, Puonti O and Iglesias JE (2024), unknown publication 1eca3a2c-67fb-4734-beb1-37110b215bf5, doi:10.1007/978-3-031-73480-9_16

Hu X, Sorby-Adams A, Barkhof F, Kimberly WT, Puonti O and Iglesias JE (2024), unknown publication c1d85fa5-7135-4183-8087-2e28f52aea4c, doi:10.1007/978-3-031-73967-5_10

Liu P, Puonti O, Sorby-Adams A, Kimberly WT and Iglesias JE (2024), unknown publication 6b84f33f-a8c4-485e-bc7b-8e5156656d13, doi:10.1007/978-3-031-72390-2_63

Zeng X, Puonti O, Sayeed A, Herisse R, Mora J, Evancic K, Varadarajan D, Balbastre Y, Costantini I, Scardigli M, Ramazzotti J, DiMeo D, Mazzamuto G, Pesce L, Brady N, Cheli F, Saverio Pavone F, Hof PR, Frost R, Augustinack J, Van der Kouwe A, Eugenio Iglesias J and Fischl B (2024), 'Segmentation of supragranular and infragranular layers in ultra-high-resolution 7T ex vivo MRI of the human cerebral cortex', Cerebral Cortex, 34(9):1-13, doi:10.1093/cercor/bhae362

Gurr C, Splittgerber M, Puonti O, Siemann J, Luckhardt C, Pereira HC, Amaral J, Crisóstomo J, Sayal A, Ribeiro M, Sousa D, Dempfle A, Krauel K, Borzikowsky C, Brauer H, Prehn-Kristensen A, Breitling-Ziegler C, Castelo-Branco M, Salvador R, Damiani G, Ruffini G, Siniatchkin M, Thielscher A, Freitag CM, Moliadze V and Ecker C (2024), 'Neuroanatomical Predictors of Transcranial Direct Current Stimulation (tDCS)-Induced Modifications in Neurocognitive Task Performance in Typically Developing Individuals', The Journal of Neuroscience, 44(22):1-12

Laso P, Cerri S, Sorby-Adams A, Guo J, Mateen F, Goebl P, Wu J, Liu P, Li H, Young SI, Billot B, Puonti O, Sze G, Payabavash S, DeHavenon A, Sheth K, Rosen M, Kirsch J, Strisciuglio N, Wolterink JM, Eshaghi A, Barkhof F, Kimberly WT and Iglesias JE (2024), unknown publication 3cc10030-55d5-48b9-8a58-80b79860dc74, doi:10.1109/ISBI56570.2024.10635502

Fuglsang SA, Madsen KH, Puonti O, Siebner HR and Hjortkjær J (2024), 'Exploring an EM-algorithm for banded regression in computational neuroscience', Imaging Neuroscience, 2:1-19, doi:10.1162/imag_a_00155

Gregersen F, Eroğlu HH, Göksu C, Puonti O, Zuo Z, Thielscher A and Hanson L (2024), 'MR imaging of the magnetic fields induced by injected currents can guide improvements of individualized head volume conductor models', Imaging Neuroscience, 2:1-15, doi:10.1162/imag_a_00176

Mantell KE, Perera ND, Shirinpour S, Puonti O, Xu T, Zimmermann J, Falchier A, Heilbronner SR, Thielscher A and Opitz A (2023), 'Anatomical details affect electric field predictions for non-invasive brain stimulation in non-human primates', NeuroImage, 279:1-12, doi:10.1016/j.neuroimage.2023.120343

Hosseini S, Puonti O, Treeby B, Hanson LG and Thielscher A (2023), 'A Head Template for Computational Dose Modelling for Transcranial Focused Ultrasound Stimulation', NeuroImage, 277:1-14, doi:10.1016/j.neuroimage.2023.120227

Nielsen JD, Puonti O, Xue R, Thielscher A and Madsen KH (2023), 'Evaluating the Influence of Anatomical Accuracy and Electrode Positions on EEG Forward Solutions', NeuroImage, 277:1-20, doi:10.1016/j.neuroimage.2023.120259

Madsen MAJ, Wiggermann V, Marques MFM, Lundell H, Cerri S, Puonti O, Blinkenberg M, Christensen JR, Sellebjerg F and Siebner HR (2022), 'Linking lesions in sensorimotor cortex to contralateral hand function in multiple sclerosis: a 7 T MRI study', Brain, 145(10):3522-3535, doi:10.1093/brain/awac203

Mauri C, Cerri S, Puonti O, Mühlau M and Van Leemput K (2022), unknown publication 82b7d4ee-5281-46e1-b10b-d500c9abdc52, doi:10.1007/978-3-031-16452-1_43

Nandi T, Puonti O, Clarke WT, Nettekoven C, Barron HC, Kolasinski J, Hanayik T, Hinson EL, Berrington A, Bachtiar V, Johnstone A, Winkler AM, Thielscher A, Johansen-Berg H and Stagg CJ (2022), 'tDCS induced GABA change is associated with the simulated electric field in M1, an effect mediated by grey matter volume in the MRS voxel', Brain Stimulation, 15(5):1153-1162, doi:10.1016/j.brs.2022.07.049

Fuglsang SA, Madsen KH, Puonti O, Hjortkjær J and Siebner HR (2021), 'Mapping cortico-subcortical sensitivity to 4 Hz amplitude modulation depth in human auditory system with functional MRI', NeuroImage, 246:1-12, doi:10.1016/j.neuroimage.2021.118745

Splittgerber M, Borzikowsky C, Salvador R, Puonti O, Papadimitriou K, Merschformann C, Biagi MC, Stenner T, Brauer H, Breitling-Ziegler C, Prehn-Kristensen A, Krauel K, Ruffini G, Pedersen A, Nees F, Thielscher A, Dempfle A, Siniatchkin M and Moliadze V (2021), 'Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population', Scientific Reports, 11(1):1-15, doi:10.1038/s41598-021-00933-z

Shirinpour S, Mantell K, Li X, Puonti O, Madsen K, Haigh Z, Casillo EC, Alekseichuk I, Hendrickson T and Xu T (2021), 'New tools for computational modeling of non-invasive brain stimulation in SimNIBS', Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 14(6):1644, doi:10.1016/j.brs.2021.10.180

Eroğlu HH, Puonti O, Göksu C, Gregersen F, Siebner HR, Hanson LG and Thielscher A (2021), 'On the reconstruction of magnetic resonance current density images of the human brain: Pitfalls and perspectives', NeuroImage, 243:1-15, doi:10.1016/j.neuroimage.2021.118517

Antonenko D, Grittner U, Puonti O, Flöel A and Thielscher A (2021), 'Estimation of individually induced e-field strength during transcranial electric stimulation using the head circumference', Brain Stimulation, 14(5):1055-1058, doi:10.1016/j.brs.2021.07.001

Cerri S, Puonti O, Meier DS, Wuerfel J, Mühlau M, Siebner HR and Leemput KV (2020), 'A Contrast-Adaptive Method for Simultaneous Whole-Brain and Lesion Segmentation in Multiple Sclerosis', NeuroImage, 225:1-17, doi:10.1016/j.neuroimage.2020.117471

Puonti O, Van Leemput K, Saturnino GB, Siebner HR, Madsen KH and Thielscher A (2020), 'Accurate and robust whole-head segmentation from magnetic resonance images for individualized head modeling', NeuroImage, 219:1-17, doi:10.1016/j.neuroimage.2020.117044

Puonti O, Saturnino GB, Madsen KH and Thielscher A (2019), 'Value and limitations of intracranial recordings for validating electric field modeling for transcranial brain stimulation', NeuroImage, 208:1-14, doi:10.1016/j.neuroimage.2019.116431

Hougaard A, Nielsen SH, Gaist D, Puonti O, Garde E, Reislev NL, Iversen P, Madsen CG, Blaabjerg M, Nielsen HH, Krøigård T, Østergaard K, Kyvik KO, Madsen KH, Siebner HR and Ashina M (2020), 'Migraine with aura in women is not associated with structural thalamic abnormalities', NeuroImage: Clinical, 28, doi:10.1016/j.nicl.2020.102361

Opheim G, Puonti O, Pedersen JO, Boer VO, Kloster A, Prener M, Simonsen HJ, Paulson OB, Pinborg LH and Ganz M (2020), unknown publication 46afb1a9-c226-4154-80c6-d9774c2c6f8d

Salvador R, Biagi MC, Puonti O, Splittgerber M, Moliadze V, Siniatchkin M, Thielscher A and Ruffini G (2020), unknown publication 94fdb946-4b4b-4a52-98c8-a4ad3ad7a43b, doi:10.1007/978-3-030-45623-8_7

Andreasen SH, Andersen KW, Conde V, Dyrby TB, Puonti O, Kammersgaard LP, Madsen CG, Madsen KH, Poulsen I and Siebner HR (2020), 'Two Coarse Spatial Patterns of Altered Brain Microstructure Predict Post-traumatic Amnesia in the Subacute Stage of Severe Traumatic Brain Injury', Frontiers in Neurology, 11:1-14, doi:10.3389/fneur.2020.00800

Agn M, Munck Af Rosenschöld P, Puonti O, Lundemann MJ, Mancini L, Papadaki A, Thust S, Ashburner J, Law I and Van Leemput K (2019), 'A modality-adaptive method for segmenting brain tumors and organs-at-risk in radiation therapy planning', Medical Image Analysis, 54:220-237, doi:10.1016/j.media.2019.03.005

Farcito S, Puonti O, Montanaro H, Saturnino GB, Nielsen JD, Madsen CG, Siebner HR, Neufeld E, Kuster N, Lloyd BA and Thielscher A (2019), unknown publication 2feb9c9f-a5e4-485d-802f-a010cbfa4f9e, doi:10.1109/EMBC.2019.8857041

Saturnino GB, Puonti O, Nielsen JD, Antonenko D, Madsen KH and Thielscher A (2019), unknown publication 1c41e689-ec5e-49e8-8b86-e031e888595b, doi:10.1007/978-3-030-21293-3_1

Boayue NM, Csifcsák G, Puonti O, Thielscher A and Mittner M (2018), 'Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation', F1000Research, 7:704, doi:10.12688/f1000research.15125.2

Nielsen JD, Madsen KH, Puonti O, Siebner HR, Bauer C, Madsen CG, Saturnino GB and Thielscher A (2018), 'Automatic skull segmentation from MR images for realistic volume conductor models of the head: Assessment of the state-of-the-art', NeuroImage, 174:587-598, doi:10.1016/j.neuroimage.2018.03.001

Csifcsák G, Boayue NM, Puonti O, Thielscher A and Mittner M (2018), 'Effects of transcranial direct current stimulation for treating depression: A modeling study', Journal of Affective Disorders, 234:164-173, doi:10.1016/j.jad.2018.02.077

Cid YD, Puonti O, Platon A, Van Leemput K, Müller H and Poletti PA (2018), unknown publication ff703b89-0d9c-4e34-9255-c7d6a752acb9, doi:10.1117/12.2294004

Puonti O, Van Leemput K, Nielsen JD, Bauer C, Siebner HR, Madsen KH and Thielscher A (2018), unknown publication 0241e401-b1ca-410e-8d99-70a2a0d51499, doi:10.1117/12.2293073


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