Samo Lasic

Research Fellow

Research Interests

My main research involves advanced diffusion NMR/MRI methods for probing microstructural features of tissues, such as cell size, shape, organization, cell-membrane permeability and microcirculation. I’m particularly interested in non-invasive multidimensional diffusion encoding approaches, which allow teasing apart different tissue features and thus provide highly specific information useful in research and in clinical applications. Within the C-MORPH project at DRCMR, I’m focusing mainly on time-dependent diffusion effects in tensor-valued encoding and exploring possibilities of using these effects to access novel microstructural information

Employments

2019 – Present

Senior Researcher, DRCMR

2018 – Present

Head of Technology Development at Random Walk Imaging

2016 – 2018

Chief scientific officer at Random Walk Imaging

2014 – 2016

Vinnova (Marie-Curie) fellow - visiting reasercher at the The Danish Research Centre for Magnetic Resonance (DRCMR)

2009 – 2016

Key Account Manager and Project Manager for OncoPulse at CR Development, NMR expert at CR Competence, AB

2007 – 2009

Postdoc at Physical Chemistry, Lund University, Sweden

2002 – 2007

Collaboration with science center Hiša Eksperimentov

2001 – 2007

Assistant professor for physics at Faculty for Mathematics and Physics, University of Ljubljana, Slovenia

2001 – 2007

Leading workshops within the program for high school in-service teachers training at Faculty for Mathematics and Physics, University of Ljubljana, Slovenia

2000 – 2001

Teaching physics at the Bežigrad high school, Ljubljana, Slovenia

Education

2006

PhD in Physics, Faculty of Mathematics and Physics, University of Ljubljana, Slovenia

2001

MSc in Physics, Faculty of Mathematics and Physics, University of Ljubljana, Slovenia

Publications

Lasič S, Just N, Nilsson M, Szczepankiewicz F, Budde M and Lundell H (2025), 'Spectral principal axis system (SPAS) and tuning of tensor-valued encoding for microscopic anisotropy and time-dependent diffusion in the rat brain', Imaging Neuroscience, 3, doi:10.1162/IMAG.a.35

Lasič S, Chakwizira A, Lundell H, Westin C and Nilsson M (2024), 'Tuned exchange imaging: Can the filter exchange imaging pulse sequence be adapted for applications with thin slices and restricted diffusion?', NMR in Biomedicine, 37(11):1-22, doi:10.1002/nbm.5208

Ohene Y, Harris WJ, Powell E, Wycech NW, Smethers KF, Lasič S, South K, Coutts G, Sharp A, Lawrence CB, Boutin H, Parker GJM, Parkes LM and Dickie BR (2023), 'Filter exchange imaging with crusher gradient modelling detects increased blood-brain barrier water permeability in response to mild lung infection', Fluids and Barriers of the CNS, 20(1):1-18, doi:10.1186/s12987-023-00422-7

Chakwizira A, Westin C, Brabec J, Lasič S, Knutsson L, Szczepankiewicz F and Nilsson M (2022), 'Diffusion MRI with pulsed and free gradient waveforms: Effects of restricted diffusion and exchange', NMR in Biomedicine, 36(1):1-22, doi:10.1002/nbm.4827

Lasič S, Yuldasheva N, Szczepankiewicz F, Nilsson M, Budde M, Dall’Armellina E, Schneider JE, Teh I and Lundell H (2022), 'Stay on the Beat With Tensor-Valued Encoding: Time-Dependent Diffusion and Cell Size Estimation in ex vivo Heart', Frontiers in Physics, 10:1-19, doi:10.3389/fphy.2022.812115

Lundell H and Lasič S (2020), unknown publication 0ea94586-5945-429d-bd2d-89841c892e86, doi:10.1039/9781788019910-00012

Andersen KW, Lasič S, Lundell H, Nilsson M, Topgaard D, Sellebjerg F, Szczepankiewicz F, Siebner HR, Blinkenberg M and Dyrby TB (2020), 'Disentangling white-matter damage from physiological fibre orientation dispersion in multiple sclerosis', Brain communications, 2(2):1-14, doi:10.1093/braincomms/fcaa077

Lundell H, Lasič S, Szczepankiewicz F, Nilsson M, Topgaard D, Schneider JE and Teh I (2020), unknown publication 64026c2e-f01f-415c-b3cf-6c228f4e081c

Lasič S, Lundell H, Szczepankiewicz F, Nilsson M, Schneider JE and Teh I (2020), unknown publication 1a1255b6-cd4f-430b-a1f7-ed39a7d14ad9

Lundell H, Nilsson M, Dyrby TB, Parker GJM, Cristinacce PLH, Zhou F, Topgaard D and Lasič S (2019), 'Multidimensional diffusion MRI with spectrally modulated gradients reveals unprecedented microstructural detail', Scientific Reports, 9(1):1-12, doi:10.1038/s41598-019-45235-7

Lasič S, Lundell H, Topgaard D and Dyrby TB (2018), 'Effects of imaging gradients in sequences with varying longitudinal storage time-Case of diffusion exchange imaging', Magnetic Resonance in Medicine, 79:2228-2235, doi:10.1002/mrm.26856


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