Oliver Hulme

Research Interests

I have broad interests in the physical, social, and biological sciences. My main interest is in the brain’s reward system. Put simply: how does it work, and why? I explore mathematical and computational theories that constrain how it should work, and then test the predictions of these theories against behavioral and neuroimaging data. There are two strands to this agenda. The first asks, how do reward computations help shape behaviour to regulate the physiological systems of the body. The second strand draws on physics. I am interested in the constraints that ergodicity imposes on decision-making, and whether such considerations can also offer a unified explanatory account of a number of disparate decision-making phenomena.

Contact Details

Oliver Hulme

Senior Researcher

oliverh@drcmr.dk

Research Areas

Computational and Systems Neuroscience (Coordinator)

Research Groups

Computational Neuroscience of Reward (Leader)

See Full CV

Employments

2020 – Present	Honorary Fellow, Max-Planck UCL Centre for Computational Psychiatry & Aging
2019 – Present	External Fellow, London Mathematical Laboratory, UK
2015 – Present	Senior Researcher, Computational Neuroscience of Reward, DRCMR
2011 – 2015	Postdoctoral Researcher, DRCMR
2010 – 2011	Sessional Lecturer, University of British Columbia
2009 – 2009	Visiting Scholar, Welsh Institute of Cognitive Neuroscience
2007 – 2008	Postdoctoral Fellow in Cognitive Neuroscience, UCL

Education

2006	PhD in Neuroimaging, University College London
2002	Special Student, Harvard University
2001	MA in Physiological Sciences, Oxford University

Publications

Lopez-Yepez JS, Barta A, Martin J, Moltesen M, Woo TF, Hulme O, Demir E, Kvitsiani D (2026), 'Time-dependent deployment of medial prefrontal cortical representations in male mice', Nature Communications, 17(1)

Steinkamp S, Chaker I, Hubert F, Meder D, Hulme OJ (2026), 'Computational parametric mapping of functional neuroimaging data', Imaging Neuroscience, 4

Steinkamp S, Meder D, Hulme O (2025), unknown publication f9440cce-2000-4a58-af16-3b6753e8f6fb

Ghaderi-Kangavari A, Hulme O, Steinkamp S, Siebner HR, Meder D (2025), unknown publication 77d661ae-c7f3-4246-a988-9f5c86deb4eb

Steinkamp S, Skjold B, van der Weij MEC, Connaughton C, Peters O, Hulme O (2025), unknown publication 9273003b-6ce8-4bba-948e-1d7de20a740f

Steinkamp S, Meder D, Hulme O (2025), unknown publication 77486d69-3b75-47af-a18a-f7a0637967bf

Ghaderi-Kangavari A, Hulme O, Steinkamp S, Siebner HR, Meder D (2025), unknown publication bc636279-ab42-482b-a9ea-18047f170c47

Meder D, Hulme OJ, Siebner HR (2025), unknown publication 2a7fa9c6-cf16-446a-9a5b-68a35518e797

Steinkamp S, Meder D, Hulme O (2024), unknown publication ea34f1ff-f824-453e-b758-3a50dbc0de77

Demnitz N, Hulme OJ, Siebner HR, Kjaer M, Ebmeier KP, Boraxbekk C, Gillan CM (2023), 'Characterising the covariance pattern between lifestyle factors and structural brain measures', Neurobiology of Aging, 131:115-123

Steinkamp S, Chaker I, Hubert F, Meder D, Hulme O (2023), unknown publication f477c349-86b0-443f-a5fb-0c35d8043b23

Steinkamp S, Chaker I, Hubert F, Meder D, Hulme O (2023), unknown publication 3ac5eb09-5c8c-43b2-bd6d-b19f2ebcb101

Demnitz N, Hulme O, Siebner HR, Kjaer M, Ebmeier KP, Boraxbekk C, Gillan C (2023), unknown publication 6b79255c-89bd-459f-a078-b80c4c92a937

Hulme OJ, Roulston B, Overgaard M (2023), 'Does report modality modulate psychophysical sensitivity?', Frontiers in Psychology, 14:1226588

Steinkamp S, Chaker I, Hubert F, Meder D, Hulme O (2022), unknown publication 6653af33-2ad8-4568-bc5c-b4925ff61c33

López-Yépez JS, Martin J, Hulme O, Kvitsiani D (2021), 'Choice history effects in mice and humans improve reward harvesting efficiency', PLOS Computational Biology, 17(10):1-33

Meder D, Rabe F, Morville T, Madsen KH, Koudahl MT, Dolan RJ, Siebner HR, Hulme OJ (2021), 'Ergodicity-breaking reveals time optimal decision making in humans', PLOS Computational Biology, 17(9):1-25

Morville T, Madsen KH, Siebner HR, Hulme OJ (2021), 'Reward signalling in brainstem nuclei under fluctuating blood glucose', PLOS ONE, 16(4):1-15

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizeau J, Hulme OJ, Billig AJ, Litvak V, Price CJ, Moran RJ, Lambert C (2020), 'Second waves, social distancing, and the spread of COVID-19 across the USA', Wellcome Open Research, 5(103):1-39

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizeau J, Hulme OJ, Billig AJ, Litvak V, Moran RJ, Price CJ, Lambert C (2020), 'Dynamic causal modelling of COVID-19', Wellcome Open Research, 5(89):1-46

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizeau J, Hulme O, Billig AJ, Litvak V, Price CJ, Moran RJ, Lambert C (2020), 'Testing and tracking in the UK: A dynamic causal modelling study [version 1; peer review: 1 approved with reservations, 1 not approved]', Wellcome Open Research, 5(144):1-24

Faranda D, Pérez Castillo I, Hulme O, Jezequel A, Lamb JSW, Sato Y, Thompson EL (2020), 'Asymptotic estimates of SARS-CoV-2 infection counts and their sensitivity to stochastic perturbation', Chaos, 30(5):1-10

van der Vegt JPM, Hulme OJ, Madsen KH, Buhmann C, Bloem BR, Münchau A, Helmich RC, Siebner HR (2020), 'Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson's disease', NeuroImage: Clinical, 28:1-8

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizeau J, Hulme OJ, Billig AJ, Litvak V, Price CJ, Moran RJ, Costello A, Pillay D, Lambert C (2020), 'Effective immunity and second waves', Wellcome Open Research, 5:1-27

Hulme OJ, Morville T, Gutkin B (2019), unknown publication cb7d13b1-4b4e-4459-b4bf-eb0f24c96740

Meder D, Rabe F, Morville T, Madsen KH, Koudahl MT, Dolan R, Siebner HR, Hulme O (2019), unknown publication 87548f29-24a1-4276-98f7-12168b3513c3

Meder D, Rabe F, Morville T, Madsen KH, Koudahl MT, Dolan R, Siebner HR, Hulme O (2019), unknown publication 0a5c89a5-ffbc-4618-a99b-ecc005a33ae4

Hulme OJ, Kvitsiani D (2019), 'Extending models of "How Foraging Works"', Behavioral and Brain Sciences, 42

Meder D, Rabe F, Morville T, Siebner HR, Hulme OJ (2018), unknown publication ead10821-e276-4c0d-9fa3-7c8b83d83bc2

Christensen BJ, Schmidt JB, Nielsen MS, Tækker L, Holm L, Lunn S, Bredie WLP, Ritz C, Holst JJ, Hansen T, Hilbert A, le Roux CW, Hulme OJ, Siebner H, Morville T, Naver L, Floyd AK, Sjödin A (2018), 'Patient profiling for success after weight loss surgery (GO Bypass study)', Contemporary Clinical Trials Communications, 10:121-130

Hallsson BG, Siebner HR, Hulme OJ (2018), unknown publication 3226c775-6e43-4753-94a1-d16b8a977de7

Meder D, Kolling N, Verhagen L, Wittmann MK, Scholl J, Madsen KH, Hulme OJ, Behrens TEJ, Rushworth MFS (2017), 'Simultaneous representation of a spectrum of dynamically changing value estimates during decision making', Nature Communications, 8(1942)

Friis-Olivarius M, Hulme OJ, Skov M, Ramsøy TZ, Siebner HR (2017), 'Imaging the Creative Unconscious', Scientific Reports, 7:1-8

Morville T, Siebner HR, Hulme OJ (2017), unknown publication 5d8decb4-e050-4a11-8bbc-37d584bdae79

Meder D, Kolling N, Verhagen L, Wittmann MK, Madsen KH, Hulme OJ, Behrens TE, Siebner HR, Rushworth MF (2017), unknown publication 13f87e5a-3c95-4328-921d-e7c07a19afb6

Morville T, Siebner HR, Hulme OJ (2017), unknown publication b1b5fae8-a93c-482e-a092-00c3fa16ff21

Meder D, Kolling N, Verhagen L, Wittmann MK, Scholl J, Madsen KH, Hulme OJ, Behrens TE, Rushworth MFS (2017), unknown publication 51d52e8e-b8bc-469f-9565-0552612efe22

Hulme OJ, Baladi Nejad A, Haren T, Henningsson S, Madsen KH, Siebner HR (2016), unknown publication 58693283-8612-40ef-9123-c55e37c524be

Meder D, Madsen KH, Hulme O, Siebner HR (2016), 'Chasing probabilities - Signaling negative and positive prediction errors across domains', NeuroImage, 134:180-191

Meder D, Kolling N, Verhagen L, Wittmann MK, Madsen KH, Hulme OJ, Behrens TE, Rushworth MF (2016), unknown publication 1bb0cedb-1fdb-4c82-8248-0f7cb0ac50ae

Meder D, Haagensen BN, Hulme O, Morville T, Gelskov S, Herz DM, Diomsina B, Christensen MS, Madsen KH, Siebner HR (2016), 'Tuning the Brake While Raising the Stake', Neuroscience Journal, 36(19):5417-5426

Morville T, Hulme OJ (2016), unknown publication 71c5d32b-8911-4f74-9333-dc10d20d7a99

Hulme OJ, Skov M, Chadwick MJ, Siebner HR, Ramsøy TZ (2014), 'Sparse encoding of automatic visual association in hippocampal networks', NeuroImage, 102 Pt 2:458-464

Chumbley JR, Hulme O, Köchli H, Russell E, Van Uum S, A Pizzagalli D, Fehr E (2014), 'Stress and reward', Physiology and Behavior, 131:33-40

Herz DM, Christensen MS, Bruggemann N, Hulme OJ, Ridderinkhof KR, Madsen KH, Siebner HR (2014), 'Motivational tuning of fronto-subthalamic connectivity facilitates control of action impulses', Neuroscience Journal, 34(9):3210-3217

Meder D, Haagensen BN, Morville T, Gelskov SA, Herz D, Diomsina B, Christensen MS, Madsen KH, Hulme O, Siebner HR (2014), unknown publication bc9f6e33-2bb1-4a5e-880b-2c018dcd0381

Herz DM, Siebner HR, Hulme OJ, Florin E, Christensen MS, Timmermann L (2014), 'Levodopa reinstates connectivity from prefrontal to premotor cortex during externally paced movement in Parkinson's disease', NeuroImage, 90:15

Morville T, Hulme O, Keramati M, Gutkin B, Siebner HR (2014), unknown publication 0fe6fb8a-406b-4e58-a94b-4b288b00e808

van der Vegt JPM, Hulme OJ, Zittel S, Madsen KH, Weiss MM, Buhmann C, Bloem BR, Münchau A, Siebner HR (2013), 'Attenuated neural response to gamble outcomes in drug-naive patients with Parkinson's disease', Brain, 136(Pt 4):1192-1203

Meder D, Haagensen BN, Morville T, Gelskov SA, Herz D, Christensen MS, Madsen KH, Hulme O, Siebner HR (2013), unknown publication 15f24484-1f88-42d2-b375-9771c893f01e

Kirk U, Skov M, Hulme O, Christensen MS, Zeki S (2009), 'Modulation of aesthetic value by semantic context: An fMRI study', NeuroImage, 44(3):1125-1132

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