Naiara Demnitz

Research Fellow

Research Interests

The overarching aim of my work is to understand how modifiable lifestyle factors can help promote healthy brain ageing. To that end, my research combines magnetic resonanceimaging (MRI) and neuropsychological assessments to characterise the relationshipbetween lifestyle factors such as physical activity and mobility, and the brain structure andfunction of older adults.

Employments

2024 – Present

Research Fellow at DRCMR

2020 – 2023

Postdoc at DRCMR

2019 – 2020

Atlantic Fellow for Equity in Brain Health, Global Brain Health Institute, Trinity College Dublin

2018 – 2019

Postdoc at the University of Oxford

2014 – 2015

Research Assistant at the University of Oxford

Education

2019

PhD in Psychiatry, University of Oxford

2014

MSc in Cognitive Neuroscience, University College London

2013

BSc in Experimental Psychology, University of Bristol

Publications

Gonzalez-Gomez R, Demnitz N, Coronel C, Gates AT, Kjaer M, Siebner HR, Boraxbekk C and Ibanez AM (2026), 'Randomized controlled trial of resistance exercise and brain aging clocks', GeroScience, doi:10.1007/s11357-026-02141-x

Roe JM, Vidal-Piñeiro D, Sørensen Ø, Grydeland H, Leonardsen EH, Iakunchykova O, Pan M, Mowinckel A, Strømstad M, Nawijn L, Milaneschi Y, Andersson M, Pudas S, Bråthen ACS, Kransberg J, Falch ES, Øverbye K, Kievit RA, Ebmeier KP, Lindenberger U, Ghisletta P, Demnitz N, Boraxbekk C, Drevon CA, Penninx B, Bertram L, Nyberg L, Walhovd KB, Fjell AM and Wang Y (2024), 'Brain change trajectories in healthy adults correlate with Alzheimer's related genetic variation and memory decline across life', Nature Communications, 15(1):1-19, doi:10.1038/s41467-024-53548-z

Karamacoska D, Heins P, Branco RM, Wallcook S, Truong A, Leung I, Sawan M, Page ZA, Borelli WV, Arroyo-Miranda ML, Demnitz N, Folarin R, Guo T, Shaaban CE, Smith A and Bartels SL (2024), 'How are early-career dementia researchers considered and supported on a national level by dementia plans and organizations?: An overview of global policy approaches', Alzheimer's & Dementia, 20(7):4727-4736, doi:10.1002/alz.13906

Bloch-Ibenfeldt M, Theil Gates A, Karlog K, Demnitz N, Kjaer M and Boraxbekk C (2024), 'Heavy resistance training at retirement age induces 4-year lasting beneficial effects in muscle strength: a long-term follow-up of an RCT', BMJ Open Sport & Exercise Medicine, 10(2):1-5, doi:10.1136/bmjsem-2024-001899

Farkhani S, Demnitz N, Boraxbekk C, Lundell H, Siebner HR, Petersen ET and Madsen KH (2024), 'End-to-end volumetric segmentation of white matter hyperintensities using deep learning', Computer Methods and Programs in Biomedicine, 245:1-11, doi:10.1016/j.cmpb.2024.108008

Demnitz N, Hulme OJ, Siebner HR, Kjaer M, Ebmeier KP, Boraxbekk C and Gillan CM (2023), 'Characterising the covariance pattern between lifestyle factors and structural brain measures: a multivariable replication study of two independent ageing cohorts', Neurobiology of Aging, 131:115-123, doi:10.1016/j.neurobiolaging.2023.07.023

Ryberg M, Boraxbekk C, Kjaer M and Demnitz N (2023), 'Effects of acute physical activity on brain metabolites as measured by magnetic resonance spectroscopy (1H-MRS) in humans: A systematic review', Heliyon, 9(10):1-13, doi:10.1016/j.heliyon.2023.e20534

Binnewies J, Nawijn L, Brandmaier AM, Baaré WF, Boraxbekk C, Demnitz N, Drevon CA, Fjell AM, Lindenberger U, Madsen KS, Nyberg L, Topiwala A, Walhovd KB, Ebmeier KP and Penninx BW (2023), 'Lifestyle-related risk factors and their cumulative associations with hippocampal and total grey matter volume across the adult lifespan: a pooled analysis in the European Lifebrain consortium', Brain Research Bulletin, 200:1-9, doi:10.1016/j.brainresbull.2023.110692

De Looze C, Demnitz N, Knight S, Carey D, Meaney J, Kenny RA and McCrory C (2023), 'Examining the Impact of Socioeconomic Position Across the Life Course on Cognitive Function and Brain Structure in Healthy Aging', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 78(6):890-901, doi:10.1093/gerona/glad068

Nyberg L, Andersson M, Lundquist A, Baaré WFC, Bartrés-Faz D, Bertram L, Boraxbekk C, Brandmaier AM, Demnitz N, Drevon CA, Duezel S, Ebmeier KP, Ghisletta P, Henson R, Jensen DEA, Kievit RA, Knights E, Kühn S, Lindenberger U, Plachti A, Pudas S, Roe JM, Madsen KS, Solé-Padullés C, Sommerer Y, Suri S, Zsoldos E, Fjell AM and Walhovd KB (2022), 'Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates', Cerebral Cortex, 33(9):5075-5081, doi:10.1093/cercor/bhac400

Lövdén M, Pagin A, Bartrés-Faz D, Boraxbekk C, Brandmaier AM, Demnitz N, Drevon CA, Ebmeier KP, Fjell AM, Ghisletta P, Gorbach T, Lindenberger U, Plachti A, Walhovd KB and Nyberg L (2023), 'No moderating influence of education on the association between changes in hippocampus volume and memory performance in aging', Aging brain, 4:1-9, doi:10.1016/j.nbas.2023.100082

De Looze C, Williamson W, Demnitz N, O'Connor D, Hernández B and Kenny RA (2022), 'Physical function, an adjunct to brain health score for phenotyping cognitive function trajectories in older age: Findings from the Irish Longitudinal Study on Ageing (TILDA)', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 77(8):1593-1602, doi:10.1093/gerona/glac024

Brugulat-Serrat A, Chen Y, Demnitz N, Ashour A, Adrion E, Ilinca S, Kinchin I, Almirall-Sanchez A, Öz D, Karanja W, Pintado M, Rogers N, Browning A, Petkuté I and Lawlor B (2022), unknown publication 67ba626d-46a1-4eb1-8298-393b14deec6d, doi:10.1002/gps.5710

Stathi A, Greaves CJ, Thompson JL, Withall J, Ladlow P, Taylor G, Medina-Lara A, Snowsill T, Gray S, Green C, Johansen-Berg H, Sexton CE, Bilzon JLJ, DeKoning J, Bollen JC, Moorlock SJ, Western MJ, Demnitz N, Seager P, Guralnik JM, Rejeski WJ, Hillsdon M and Fox KR (2022), 'Effect of a physical activity and behaviour maintenance programme on functional mobility decline in older adults: the REACT (Retirement in Action) randomised controlled trial', The Lancet Public Health, 7(4):316-326, doi:10.1016/S2468-2667(22)00004-4

Peeters G, Katelekha K, Lawlor B and Demnitz N (2022), 'Sex differences in the incidence and prevalence of young-onset Alzheimer's disease: A meta-analysis', International Journal of Geriatric Psychiatry, 37(1):1-9, doi:10.1002/gps.5612

Demnitz N, Stathi A, Withall J, Stainer C, Seager P, De Koning J, Esser P, Wassenaar T, Dawes H, Brooks J, Ebmeier KP, Johansen-Berg H and Sexton CE (2021), 'Hippocampal maintenance after a 12-month physical activity intervention in older adults: The REACT MRI study', NeuroImage: Clinical, 35:1-9, doi:10.1016/j.nicl.2021.102762

Demnitz N, Madsen KS, Johnsen LK, Kjaer M, Boraxbekk C and Siebner HR (2021), 'Right-left asymmetry in corticospinal tract microstructure and dexterity are uncoupled in late adulthood', NeuroImage, 240:1-9, doi:10.1016/j.neuroimage.2021.118405


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